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GLP 1 receptor agonists may dampen libido, likely through brain pathways tied to appetite and reward, though mechanisms remain unclear. Emerging data suggest serotonin receptor effects may play a role, but clinicians note The Thyroid Twist: How GLP 1 Agonists Are Influencing Autoimmune Thyroid Care Cureus Liraglutide vs Semaglutide GLP 1 vs GLP 1 for Weight Loss GLP 1 Medications: The Good, The Bad, & The Ugly! Weight Loss Blog Dr. Tague's Center for Nutrition Kansas City & Topeka Let's break the drug tirzepatide down using this mnemonic cloud! Tirzepatide is a GLP 1 and GIP agonist. But what exactly is glucagon like peptide (GLP 1) and gastric inhibitory polypeptide (GIP)?
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Nice shoes!
Size: 11, Color: Black Full Grain
I bought them in black and I like them so much I will be buying the brown soon. They fit true to size and are comfortable and stylish. I like the clean simplicity. They're basically a dressy sneaker which is perfect for my job's 'dress code'. Yet they're stylish enough to be worn weekends or a night out. They seemed just a touch stiff out of the box but IMO that's completely normal and fine - after just a couple days of wearing them they are breaking in nicely. No complaints on that. They seem to be of very high quality and I'm very happy with them.
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Reviewed in the United States on February 8, 2026
★★★★★ 5
Good shoes!!!!!
Size: 10, Color: Tan Full Grain
They are comfortable, they fit, great style. I bought blue, brown and black shoes.
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Reviewed in the United States on August 18, 2025
★★★★★ 5
Great Product
Size: 13, Color: Black Full Grain
2nd Johnston & Murphy comfortable and stylish.
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Reviewed in the United States on December 26, 2025
★★★★★ 5
Great shoes for business casual, corporate travel
Size: 8.5, Color: White Full Grain
Fit true to size
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Reviewed in the United States on December 30, 2025
★★★★★ 5
Very Comfortable Shoes
Size: 11, Color: Black Full Grain
Were purchased as a gift and the wearer says they are the most comfortable shoes he has
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