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GLP 1 and its derived peptides mediate pain relief through direct TRPV1 inhibition without affecting thermoregulation Experimental & Molecular Medicine A biobehavioral model found that weight suppression lower leptin reduced GLP 1 response lower satiation, which is associated with larger binge eating episodes in women with Bulimia Nervosa., The rapid rise of GLP 1 receptor agonists presents a complex dilemma for clinicians managing patients with eating disorders. While these medications show potential in reducing binge eating behaviors by targeting brain reward GLP 1 medications are known for helping with weight loss, but new research suggests they may also impact brain health. UCSF scientists are exploring the link between GLP 1s, dementia, and addiction. Some studies The Louisiana Senate Health and Welfare Committee debated a bill that would require Medicaid to cover FDA approved weight loss medications for its recipients. See our bio link to learn more.